The Effects of Jwa Kum-Whan and Soo Ryeon-Whan on the Hyperlipidemia in Rats
published in 2005. 6.
Abstracts
Objectives : By examining the effects of Jwa Kum-Whan composed of Coptidis Rhizoma and Evodiae Fructus by the ratio of 6:1 the effects of Soo Ryeon-Whan and composed of Coptidis Rhizoma and Evodiae Fructus by the ratio of 1:1 on hyperlipidemia, the present study attempted to reveal the change of effects based on the ratio of combination. Methods : Jwa Kum-Whan and Soo Ryeon-Whan were injected to rats suffered from induced hyperlipidemia, and then its influence on lipid. During the cultivation of hepatocytes, Jwa Kum-Whan and Soo Ryeon-Whan were added to culture media, and the expression of the enzymes relevant to fat metabolism of hepatocytes was examined. Results : 1. Jwa Kum-Whan significantly decreased total cholesterol(Tc), triglyceride(TG), and LDL-cholesterol(LDLc) of rats suffering from hyperlipidemia induced by high cholesterol diet. Soo Ryeon-Whan decreased LDLc, but had no significant on Tc and TG. 2. Jwa Kum-Whan increased the expression of cholesterol esterase, LDL-receptor, diacylglycerol acyltransferase (DGAT), acylCoA-cholesterol-acyltransferase (ACAT), peroxisome proliferator activated receptor gamma
Keyword
- Jwa Kum-Whan
- Soo Ryeon-Whan
- Coptidis Rhizoma
- Evodiae Fructus
- hyperlipidemia
Analytical Information
IPC | A61K 36/718, A61K 36/754, A61P 3/06 |
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Analytical Keyword | Coptidis Rhizoma=Coptis chinensis Franch; Evodiae Fructus=Evodia rutaecarpa Benth.; hyperlipidemia; Jwa Kum-Whan; Soo Ryeon-Whan; total cholesterol(Tc); triglyceride(TG); LDL-cholesterol; high cholesterol diet |
Herb keywrd | Coptidis Rhizoma=Coptis chinensis Franch; Evodiae Fructus=Evodia rutaecarpa Benth. |
Prescription keywrd | Jwa Kum-Whan; Soo Ryeon-Whan |
Disease keywrd | hyperlipidemia |
Etc. keywrd | total cholesterol(Tc); triglyceride(TG); LDL-cholesterol; high cholesterol diet |
Related Herbs (All 164건) | Gyeonyuk(犬肉); Goda(苦茶); Goga(穀芽)A; Gongpohwang(貢蒲黃); Gwache(瓜蒂); Gwachemal(瓜蒂末); Gu(狗); Gu(蛷); Gu(韭); Guchae(韭菜); Gupihyejeo(久皮鞋底); Geumbak(金箔); Geumseonwa(金線蛙)A; Geumseonwa(金線蛙)B; Geumseonwa(金線蛙)C |
Country | kor |
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Publisher | The Korea Association of Herbology |
Language | Korean |
KJTK Publish Information | Volume 1. 2007. 12. 28 |
TKOI
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TKOI:KTKP-TSS-0000045809 |